In vitro anthelmintic and antimicrobial activity of synthesized fluoro and nitro substituted N-[(Z)-phenylmethylidene]-1,3-benzothiazol-2-amine and its derivatives

摘要

The Intention of doing this research work is to develop some new chemical compounds which can show their action on both parasitic worms and microbes which causing disease. So a serious of substituted Schiff bases i.e. N-[(Z)- phenylmethylidene]-1,3-benzothiazol-2-amine were synthesized from fluoro and nitro substituted Benzothiazol-2- amine with different aryl aldehydes under conventional method. The structure for compounds has been determined by Physical and spectral data like M.P, IR by KBr method, 1H-NMR & Mass spectroscopy. All the compounds are evaluated for their In-vitro anthelmintic and anti-microbial activity by standard methods.