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Formulation and Evaluation of Fast Disintegrating Tablets of Caffeine by Using Effervescent Formulation Approach

机译:泡腾剂法快速制备咖啡因片及其评价

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In recent decades, a variety of pharmaceutical research has been conducted to develop new dosage forms. Among them, the fast disintegrating tablet (FDTs) is one of the most widely employed commercial products to facilitate ease of medication. Upon introduction into the mouth, these tablets dissolve or disperse in the mouth in the absence of additional water and the active pharmaceutical ingredients are readily released from the dosage form. The popularity and usefulness of these formulations resulted in development of several ODT technologies. These tablets are convenient for young children, elderly and patients with swallowing difficulties, and in situations where a potable liquid (water) is not available. The popularity and usefulness of these formulations resulted in development of several ODT technologies. Caffeine acts as a central nervous system stimulant produces increased wakefulness, faster and clearer flow of thought, increased focus, and better general body coordination. Soluble effervescent tablets get dissolved quickly when put in water to give a solution which can be easily consumed by patients with temporarily warding off drowsiness and restoring alertness. The present investigation describes the formulation methodology, evaluation parameters and future aspects of fast disintegrating tablets (FDTs).
机译:在最近的几十年中,已经进行了各种药物研究以开发新剂型。其中,快速崩解片(FDT)是使用最广泛的可简化药物治疗的商业产品之一。引入口腔后,这些片剂在没有额外水的情况下溶解或分散在口腔中,并且活性药物成分易于从剂型中释放。这些配方的流行和实用性导致了几种ODT技术的发展。这些片剂对于年幼的儿童,老人和吞咽困难的患者以及在没有可用液体(水)的情况下都很方便。这些配方的流行和实用性导致了几种ODT技术的发展。咖啡因是中枢神经系统的刺激物,可提高清醒度,加快思维速度并使其清晰,集中注意力并改善全身协调性。溶于水的泡腾片放入水中后迅速溶解,形成一种溶液,患者可以暂时服用以减轻嗜睡和恢复机敏性。本研究描述了快速崩解片(FDT)的配制方法,评估参数和未来方面。

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