Anti-inflammatory and analgesic activities of the Sauropus androgynus(L)Merr. (Euphorbiaceae) Plant in experimental animal models

摘要

The present study was aimed to investigate the analgesic and anti-inflammatory effect of the aqueous and ethanolic extract of leaves of Sauropus androgynus in Wister rats. Sauropus androgynus leaf extracts (100, 200 and 400 mg/kg body weight) were evaluated for its anti-inflammatory activity by carrageenan induced rat paw edema and analgesic activity by Hot plate Test. The extracts were found to posses significant anti-inflammatory effect in ethanolic extract than when compared to aqueous extract. Significant reduction in paw edema and significant increased reaction time were observed at a dosage of 400 mg/kg/body weight