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Soft tissue chondroma of the index finger: Clinical, histological and radiological findings in a unique case

机译:食指软组织软骨瘤:独特病例的临床,组织学和影像学检查结果

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A chondroma is a benign, slow-growing cartilaginous tumor. When arising in the medullary cavity of a bone it is referred to as an enchondroma-a very common bone tumor. When occurring in soft tissue without any connection to bone, which is extremely rare, it is known as a soft-tissue chondroma (STC). A 38-year-old female presented with a 2- year history of right index finger pulp swelling in the absence of trauma. On physical examination a firm, immobile nodule, approximately 1 cm in diameter, was observed on the palmar side of the right index finger. The overlying skin was normal. Plain X-ray showed a dense, soft tissue shadow without calcification in the right index finger pulp, but the adjacent bones were intact. MRI showed a 1-cm diameter, well-demarcated lesion with intermediate signal intensity on T1-weighted images and high signal intensity on T2-weighted images. MRI also showed that the tumor had no bony involvement and that the adjacent bones were normal. Histopathological examination of the biopsy specimen showed lobules of mature hyaline cartilage with chondrocytes in the lacunae in the dermal and subdermal layers. Mitotic figures and an increase in cellular atypism were not observed. Based on the histopathological and radiological findings, the mass was thought to be an STC and total excision was performed. Examination of the excised mass confirmed the diagnosis of STC. STC should be considered in patients with a slowly growing, mildly painful cutaneous mass.
机译:软骨瘤是一种良性,生长缓慢的软骨肿瘤。当出现在骨骼的髓腔中时,称为内生软骨瘤-一种非常常见的骨肿瘤。当发生在与骨骼没有任何连接的软组织中时,这种情况极为罕见,这就是所谓的软组织软骨瘤(STC)。一位38岁的女性在没有外伤的情况下有2年的右手食指肿胀的病史。进行身体检查时,在右手食指的手掌侧观察到了直径约1 cm的坚固,固定的结节。上面的皮肤是正常的。普通X射线在右手食指上显示出密集,柔软的组织阴影,而无钙化现象,但相邻的骨骼完好无损。 MRI显示直径为1厘米的病灶,边界清晰,在T1加权图像上信号强度中等,在T2加权图像上信号强度高。 MRI还显示该肿瘤无骨累及,相邻骨骼正常。活检标本的组织病理学检查显示,在真皮层和皮下层的腔中,成熟透明软骨小叶中带有软骨细胞。没有观察到有丝分裂图和细胞异型性的增加。根据组织病理学和放射学发现,该肿块被认为是STC,并进行了全切除。检查切除的肿块证实了STC的诊断。对于缓慢增长,轻度疼痛的皮肤肿块,应考虑使用STC。

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