Multidisciplinary care for better clinical outcomes: role of pharmacists in medication management

摘要

The global population aged 60 years or older was 962 million in 2017—double the number in 1980—and is expected to double again by 2050. 1 More significantly, older persons are expected to outnumber children younger than 10 years and adolescents in 2030 and 2050, respectively. 1 The ageing population is a global issue and Hong Kong is not exempt. Despite the persistently low fertility rate, it is projected that the dependency ratio, defined as the number of persons aged under 15 years and 65 years or over per 1000 persons aged 15 to 64 years, will increase from 397 in 2016 to 844 in 2066. 2 A longer life can be an incredibly valuable resource, 3 provided it is accompanied by good health. 4 Nonetheless, over 70% of Hong Kong elderly people have chronic illnesses, ranging from cardiovascular problems to oncological diseases. 5 It is also estimated that approximately 40% of the elderly population in Hong Kong take more than five medications every day. 6 Given the substantial risk of drug-related problems among elderly people, the medication management for elderly patients in Hong Kong needs to be addressed. Hong Kong has a largely government-based subsidised health care system, with more than 90% of secondary and tertiary care provided by physician consultations in the public sector; a general out-patient clinic visit lasts an average of 3 to 5 minutes. 7 It is difficult to provide adequate counselling and medication review during such a short time. In 2013, The University of Hong Kong conducted a study to analyse the nature of pharmaceutical services for elderly patients in Hong Kong. Although the study identified a number of services related to elderly patients, the lack of solid data concerning medication errors and effectiveness of pharmaceutical services 6 made it difficult to understand medication management among the group. Although there has been no formal study of medication management in an elderly population, research has clearly established a strong relationship between polypharmacy and negative clinical consequences, including but not limited to adverse drug reactions, drug-drug interactions, and non-compliance. 8 Appropriate medication management may minimise drug wastage that also places a significant economic burden on the health care system. Multidisciplinary team: role of pharmacists The Institute of Medicine (IOM) declared that “health care professionals should be educated to deliver patient-centered care as members of an interdisciplinary team”. 9 The IOM also stated that patients receive better and safer care when health care professionals work effectively as a team, understanding each other’s roles and communicating effectively. 9 Pharmacists are known to be drug experts and therefore in a good position to prevent drug-related problems, which are a particular risk for the elderly patients. 10 11 12 Different reviews have demonstrated the value of pharmacists in improving the overall quality of prescribing and consequently minimising drug-related problems. The outreach programme led by The Chinese University of Hong Kong has also demonstrated that pharmacists could improve blood pressure control and heart failure symptoms in addition to addressing the many drug-related problems faced by the community elderly population. 13 14 In this issue, Chiu et al 15 show that a pharmacist-led medication review programme was one of the important strategies to enhance the safety and quality of prescription among elderly patients in hospital. The study revealed that over half of the subjects were prescribed inappropriate medications. The authors stated that most inappropriate medication use was related to effectiveness, dosage, and directions. It highlighted the impact of a systematic pharmacist-led medication review programme on geriatric patients in the hospital setting. The potential cost-savings from avoidance of inappropriate medication use and unscheduled hospital readmission can be significant in the long term. Pharmacists should therefore be more proactive, both directly and collaboratively, in the teams caring for elders in order to optimise pharmacotherapy. Despite their value, the pharmacist-to-population ratio in Hong Kong was only 1 per 2774 population in 2016, 16 a ratio that is significantly less than that reported by the World Health Organization (1 per 1000) 17 and other upper-middle–income and high-income countries. 18 The lack of human resources in addition to the lack of government support may explain the underutilisation of clinical pharmacy services in Hong Kong. It was only recently that the government acknowledged the need to strengthen clinical pharmacy services for elderly persons living in elderly homes. 19 Furthermore, many old-age home managers fail to appreciate that the role of the pharmacist extends beyond just dispensing drugs and instead consider employment of nurses or health care assistants to be a higher priority. 6 Unless there is a more widespread appreciation of th