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Data on cytotoxic activity of an Artemisia annua herbal preparation and validation of the quantification method for active ingredient analysis

机译:一种 Annemisia annua 草药制剂的细胞毒性活性数据以及用于活性成分分析的定量方法的验证

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摘要

The data in this article contain supporting information for the research manuscript entitled “Antitumor activity of anArtemisia annuaherbal preparation and identification of active ingredients” by Lang et?al. [1]. MomundoArtemisia annuaextract and an acetonitrile fraction thereof induce apoptosis in MDA-MB-231 triple negative breast cancer cells as shown by XTT viability assay and induction of the subG0/G1cell population by flow cytometric analysis. Furthermore, the HPLC-DAD method used to characterize theArtemisia annuaherbal preparation as well as UHPLC-MS/MS method used to quantify the most abundant compounds in the extract and its validation are presented.
机译:本文中的数据包含Lang等人的题为“无花果蒿的抗肿瘤活性和活性成分的鉴定”的研究手稿的辅助信息。 [1]。如XTT活力测定所示,桃核蒿提取物及其乙腈级分在MDA-MB-231三阴性乳腺癌细胞中诱导凋亡,并通过流式细胞术分析诱导subG0 / G1细胞群。此外,还介绍了用于表征青蒿制剂的HPLC-DAD方法以及用于定量提取物中最丰富的化合物的UHPLC-MS / MS方法及其验证。

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