EXTENDING THE DEBATE ON POOR RESPONSE TO HEPATITIS B VIRUS VACCINATION IN CHILDREN WITH CELIAC DISEASE: WHICH QUESTION REMAINS?

摘要

Dear EditorA poorer response to hepatitis B vaccination, in coeliac subjects, compared to healthy subjects, has been largely debated. Almost all authors postulated that human leukocyte antigen (HLA) genotype DQ2, found in 90 - 95% of coeliac patients, could represent the main cause in determining the impaired antibody response to recombinant HBV vaccine (1), as well as observed also in healthy not responder subjects.