The GPIIbIIIa antagonist drugs eptifibatide and tirofiban do not induce activation of apoptosis executioner caspase-3 in resting platelets but inhibit caspase-3 activation in platelets stimulated with thrombin or calcium ionophore A23187 | Haematologica

Valery Leytin; Asuman Mutlu; Sergiy Mykhaylov; David J. Allen; Armen V. Gyulkhandanyan; John Freedman

首页> 外文期刊>Haematologica >The GPIIbIIIa antagonist drugs eptifibatide and tirofiban do not induce activation of apoptosis executioner caspase-3 in resting platelets but inhibit caspase-3 activation in platelets stimulated with thrombin or calcium ionophore A23187 | Haematologica

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The GPIIbIIIa antagonist drugs eptifibatide and tirofiban do not induce activation of apoptosis executioner caspase-3 in resting platelets but inhibit caspase-3 activation in platelets stimulated with thrombin or calcium ionophore A23187 | Haematologica

机译：GPIIbIIIa拮抗剂药物埃替非巴肽和替罗非班在静息血小板中不诱导凋亡执行者caspase-3活化，但在凝血酶或钙离子载体A23187刺激的血小板中却抑制caspase-3活化。血液学

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《Haematologica》 |2009年第12期|共2页
作者
Valery Leytin; Asuman Mutlu; Sergiy Mykhaylov; David J. Allen; Armen V. Gyulkhandanyan; John Freedman;
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中图分类血液及淋巴系疾病;
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1. Calcium Signaling in Human Platelet Aggregation Mediated by Platelet Activating Factor and Calcium Ionophore, A23187 [J] . Huma Rasheed, Afshin Hasan Tirmizi, Farah Salahuddin, Journal of Biological Sciences . 2004,第2期

机译：血小板活化因子和钙离子载体介导的人类血小板聚集中的钙信号传导，A23187
2. Biosynthesis of platelet-activating factor by cultured rat Kupffer cells stimulated with calcium ionophore A23187 [J] . A Siafaka-Kapadai, D J Hanahan, M S Olson, The biochemical journal . 1989,第3期

机译：钙离子载体A23187刺激的大鼠Kupffer细胞对血小板活化因子的生物合成
3. Activation of caspases-9, -3 and -8 in human platelets triggered by BH3-only mimetic ABT-737 and calcium ionophore A23187: Caspase-8 is activated via bypass of the death receptors [J] . MutluA., GyulkhandanyanA.V., FreedmanJ., British Journal of Haematology . 2012,第5期

机译：仅BH3模拟物ABT-737和钙离子载体A23187触发的人血小板中caspases-9，-3和-8的激活：通过绕过死亡受体来激活caspase-8。
4. Structure-Based Design, Synthesis and Evaluation of Novel Peptidic Inhibitors of Thrombin-Induced Activation of Platelets Aggregation [C] . Janet Gonzalez, Anna Babinska, Ebenezer L.V. Ewu American Peptide Symposium . 2015

机译：基于结构的设计，合成和评价血小板诱导的血小板聚集活化的激活
5. The Influence of Differential Beta Arrestin Isoform Expression on Platelet-activating Factor-Induced Cell Fate and Implications to the Onset and Progression of Necrotizing Enterocolitis. [D] . Issac, Marla Edwinna. 2013

机译：差异β抑制蛋白同工型表达对血小板活化因子诱导的细胞命运的影响及其对坏死性小肠结肠炎的发作和进展的影响。
6. The GPIIbIIIa antagonist drugs eptifibatide and tirofiban do not induce activation of apoptosis executioner caspase-3 in resting platelets but inhibit caspase-3 activation in platelets stimulated with thrombin or calcium ionophore A23187 [O] . Valery Leytin, Asuman Mutlu, Sergiy Mykhaylov, 2009

机译：GPIIbIIIa拮抗剂药物eptifibatide和tirofiban不会在静息血小板中诱导凋亡执行者caspase-3活化但会抑制凝血酶或钙离子载体A23187刺激的血小板中caspase-3活化。
7. The GPIIbIIIa antagonist drugs eptifibatide and tirofiban do not induce activation of apoptosis executioner caspase-3 in resting platelets but inhibit caspase-3 activation in platelets stimulated with thrombin or calcium ionophore A23187 [O] . Leytin, Valery, Mutlu, Asuman, Mykhaylov, Sergiy, 2009

机译：GPIIbIIIa拮抗剂药物eptifibatide和tirofiban不会在静息血小板中诱导凋亡执行者caspase-3活化，但会抑制凝血酶或钙离子载体A23187刺激的血小板中caspase-3活化。

The GPIIbIIIa antagonist drugs eptifibatide and tirofiban do not induce activation of apoptosis executioner caspase-3 in resting platelets but inhibit caspase-3 activation in platelets stimulated with thrombin or calcium ionophore A23187 | Haematologica

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