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Stress gastric ulcer after cardiac surgery: Pathogenesis risk factors and medical management

机译:心脏手术后应激性胃溃疡的发病机制及医疗管理

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Stress ulcer lesions of upper gastrointestinal tract are well recognized in patients undergoing open cardiac surgery. Gastrointestinal bleeding following cardiac surgery is infrequent with significant morbidity and mortality. The pathogenesis of mucosal lesions and subsequent haemorrhage is complex and multifactorial. The diagnosis as well as the treatment of this complication remains a challenge for surgeons. Identifying the source of bleeding can be difficult. Despite of the successful control of haemorrhage using various combinations of endoscopic and pharmacological therapies, the mortality rate remains unchanged. Benefit of routine stress ulcer prophylaxis remains controversial.
机译:在接受心脏直视手术的患者中,上消化道的应激性溃疡病灶得到了很好的认识。心脏手术后的胃肠道出血很少见,发病率和死亡率均很高。粘膜病变和随后的出血的发病机制是复杂和多因素的。这种并发症的诊断和治疗仍然是外科医生所面临的挑战。确定出血源可能很困难。尽管使用内窥镜和药物疗法的各种组合成功控制了出血,但死亡率仍然保持不变。常规预防应激性溃疡的益处仍存在争议。

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