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Second trimester hepatic rupture in a 35 year old nulliparous woman with HELLP syndrome: a case report

机译:一名35岁HELLP综合征未产妇的中期妊娠肝破裂:一例报告

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The HELLP syndrome (haemolysis, elevated liver blood tests and low platelets) is a serious complication in pregnancy characterized by haemolysis, elevated liver enzymes and low platelet count occurring in 0.5 to 0.9% of all pregnancies and in 10–20% of cases with severe preeclampsia. Hepatic capsular rupture is a rare yet dramatic complication of HELLP syndrome. The majority of cases occur in multiparous women over the age of 30. Classically it presents with acute onset right upper quadrant pain in the presence of constitutional symptoms such as vomiting and pyrexia. However, symptoms and signs are usually non specific. Spontaneous hepatic rupture can be preceded by signs of hypovolaemic shock; yet the diagnosis is infrequently made prior to emergent laparotomy. We present the case of a 35 year old nulliparous woman with a second trimester gestational hepatic rupture associated with HELLP syndrome. We briefly discuss the aetiology, diagnostic difficulties and treatment options associated with this rare presentation.
机译:HELLP综合征(溶血,肝血测试升高和血小板低下)是妊娠的严重并发症,其特征是溶血,肝酶升高和血小板计数低,发生在所有怀孕的0.5%至0.9%,重症病例中的10%至20%先兆子痫。肝荚膜破裂是HELLP综合征的一种罕见但戏剧性的并发症。大多数病例发生在30岁以上的多胎妇女中。典型的情况是,在出现呕吐和发热等体质症状时,右上腹出现急性发作性疼痛。但是,症状和体征通常是非特异性的。自发性肝破裂可伴有血容量减少性休克的迹象。然而,在急诊剖腹手术之前很少进行诊断。我们介绍了一个35岁的未产妇,伴有HELLP综合征的妊娠中期肝破裂的病例。我们简要讨论了与这种罕见表现相关的病因,诊断困难和治疗选择。

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