Acute Limphoblastic Leukemia. An Unusual Presentation and Review of the Literature

摘要

Objective: To present the case of a suckling baby with acute linfoblastic leukemia (ALL) whose initial symptom was rejection to the standing position. Clinical Case: Female suckling baby of 18 months of age, with rejection to the standing position of 4 weeks of evolution. Her weigh and her height were 9.7 kg and 82 cm respectively (h/age, w/age and w/h) in the 10 percentile; she presented pain of her right knee joint (RKJ). Polyradiculoneuropathy, myositis, and septic arthritis of RKJ was the first diagnosis. antibiotic treatment was implemented without improvement. At the fourth day she presented tumor lyses syndrome, the bone marrow aspiration showed 100% of blasts and was diagnosed ALL. Discussion: Children with ALL may present several symptoms as for example bone or joint pain. In this suckling baby, the ALL appeared with rejection to standing up, agreeing with previous studies. Conclusions: In children with bones and joints pains, with or without other clinical manifestations must be considered the ALL, as the underlying pathology.