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Treatment of persistent allergic rhinitis via acupuncture at the sphenopalatine acupoint: a randomized controlled trial

机译:通过ala蝶a穴针刺治疗持续性过敏性鼻炎:一项随机对照试验

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Allergic rhinitis is a common respiratory disease. Acupuncture is used to treat it in traditional Chinese medicine, and generally, the L120, ST2 and ST36 acupoints are selected in clinical practice. We report a new method of acupuncture at the sphenopalatine acupoint (SPA) for treatment of persistent allergic rhinitis (PAR). The effect of this treatment was investigated using two different needling depths. The efficacy of this treatment was associated with accurate stimulation of the sphenopalatine ganglion (SPG). A total of 61 patients diagnosed with PAR were randomly allocated to either the acupuncture or the sham acupuncture group. The difference between the groups was the needle depth when acupuncture was administered, which was 50?mm and 20?mm. Alteration in total nasal symptom score (TNSS) was the primary outcome. Quality of life, medication dosages and adverse events were secondary outcomes, measured using the Rhinoconjunctivitis Quality of Life Questionnaire (RQLQ). Confidence assessment was performed to evaluate data from the treatment and follow-up periods. Results were: (1) average TNSS in the treatment group was significantly lower than in the control group at week 4 (median and 25th and 75th percentiles were 5.00 (4.00, 7.00) and 8.00 (7.00, 10.00), respectively (P?
机译:过敏性鼻炎是常见的呼吸系统疾病。针灸用于中药治疗,一般在临床上选择L120,ST2和ST36穴位。我们报告针phenala(SPA)针灸治疗持续性变应性鼻炎(PAR)的一种新方法。使用两种不同的针刺深度研究了这种处理的效果。该治疗的功效与蝶ala神经节(SPG)的准确刺激有关。总共61例被诊断为PAR的患者被随机分配到针灸组或假针灸组。两组之间的差异是进行针刺时的针深,分别为50?mm和20?mm。主要症状是总鼻症状评分(TNSS)的改变。生活质量,药物剂量和不良事件是次要结果,使用鼻结膜炎生活质量调查表(RQLQ)进行测量。进行了信心评估以评估治疗和随访期间的数据。结果是:(1)在第4周,治疗组的平均TNSS显着低于对照组(中位数,第25和第75个百分位数分别为5.00(4.00,7.00)和8.00(7.00,10.00)(P < 0.001))。但是,在第12周时,两组的分数没有显着差异。 (2)与对照组相比,治疗组在第2周的生活质量(RQLQ)显着提高(得分为35.47±8.20和45.48±8.84; P <0.001); (3)在随访期间,治疗组的用药剂量明显低于对照组(3.64±1.45和6.14±2.34; P <0.05)。 (4)治疗期间两组均未观察到不良事件。这项初步研究揭示了针灸SPA预防PAR发生的深远影响。治疗组(针深度为50?mm)的TNSS明显低于对照组(针深度仅为20?mm)。我们的结果表明,直接在SPA进行针刺刺激SPG是治疗PAR的有效方法。针灸临床试验注册中心AMCTR-OOR-16000014和中国临床试验注册中心ChiCTR-IOR-16009211 2016年9月1日注册。

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