Spermatogenic and spermatotoxic effects of Telfairia occidentalis (Ugu) aqueous leaves extract in adult male Wistar rats (Rattus novergicus)

摘要

Telfairia occidentalis (TO), commonly called Pumpkin is a plant with numerous medicinal values. Here we investigated the effects of Telfairia occidentalis aqueous leaves extract on the testis of Adult Male Wistar Rats (Rattus novergicus). Thirty-Five (35) adult male rats were grouped into seven (7) containing five (n?=?5) rats in each group. Group A served as control, group B and C received 100?mg/kg body weight of Telfairia occidentalis for two and four weeks respectively, group D and E received 200?mg/kg body weight of Telfairia occidentalis for two and four weeks respectively, while group F and G received 300?mg/kg body weight of Telfairia occidentalis for two and four weeks respectively. Serum testosterone levels, testicular histomorphometry, Semen and histological analysis were observed. A dose dependent significant (P?