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What is the role of bronchial thermoplasty in the management of severe asthma?

机译:支气管热成形术在重度哮喘治疗中起什么作用?

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Asthma is a common chronic inflammatory condition of the airways. Conventional therapy comprises inhaled corticosteroid and bronchodilators as well as trigger avoidance and management of comorbid conditions. A small group remain symptomatic despite these strategies and novel therapies have been developed. Bronchial thermoplasty is a nonpharmacological therapy which targets airway smooth muscle to improve asthma control. Clinical trials to date have shown the efficacy and safety of bronchial thermoplasty with a persistent effect on extended follow up. Questions remain regarding the exact mechanism of action of bronchial thermoplasty, the cost effectiveness of the procedure and the ideal criteria for patient selection.
机译:哮喘是气道常见的慢性炎症性疾病。传统疗法包括吸入皮质类固醇和支气管扩张剂,以及避免和治疗合并症。尽管采取了这些策略并且已经开发出新的疗法,但是仍然有少数人对症治疗。支气管热成形术是一种非药物疗法,其靶向气道平滑肌以改善哮喘控制。迄今为止的临床试验表明,支气管热成形术的有效性和安全性对长期随访具有持续影响。关于支气管热成形术的确切作用机理,手术的成本效益以及患者选择的理想标准,仍然存在疑问。

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