SUBARACHNOID BLOCK; Comparison of efficacy of phenylephrine versus ephedrine in the treatment of hypotension during subarachnoid block in C-Section

摘要

Introduction: Subarachnoid block has been in practice for below umbilicalsurgery more than 110 years.1 in recent era all over the world most of cesarean sections arebeing done under subarachnoid block because of high mortality rate associated with generalanesthesia due to failed intubation and aspiration pneumonia. Objectives: To compare theefficacy of phenylephrine versus ephedrine in the treatment of hypotension during cesareansection under subarachnoid block. Study Design: Randomized control trial. Setting:Department of Anesthesiology Nishter Hospital Multan. Period: March 2014 to August 2014.Materials and Methods: A total 80 patients included in the study and patients were divided intotwo equal groups. Phenylephrine group (P group) and Ephedrine group (E group), 40 patientsin each. Results: A total of 80 (100%) patients included in the study. As concern to the age ofpatients, mean age in group E was 30.50 and standard deviation was 5.383, similarly in groupP mean age was 30.75 and SD was 5.921. As concern to the efficacy in group E, 7 were havinggood efficacy and 33 were have poor efficacy. In group P 30 had good efficacy and 10 hadpoor efficacy. P=0.000 a significant value. Conclusion: Phenylephrine is more effective thanephedrine for the treatment of hypotension due to subarachnoid block during cesarean section.