Urban rural disparity in female breast cancer incidence rate in China and the increasing trend in parallel with socioeconomic development and urbanization in a rural setting

摘要

Abstract BackgroundWorldwide breast cancer incidence correlates with socioeconomic status and increases in parallel with westernization, however urban–rural disparity and trends have not been adequately investigated in China. MethodsThe age standardized rate (ASR) of female breast cancer by population-based cancer registration was compared between urban Shijiazhuang city and rural Shexian County in relation to socioeconomic status. The increasing trend of breast cancer in Shexian County from 2000–2015 was examined using Joinpoint analysis and the correlation with gross domestic product (GDP) per capita was analyzed. ResultsIn 2012, the ASR of female breast cancer in Shijiazhuang was more than three times higher than in Shexian County (45.5/1?00?000 vs.13.8/1?00?000; P ConclusionThe incidence of breast cancer in women in China is increasing along with lifestyle westernization and changing reproductive patterns associated with socioeconomic development and urbanization. Urgent prevention measures, including the development of a healthy diet, giving birth at a younger age, an increase in breastfeeding, limiting menopause estrogen therapy, and control of alcohol consumption, are required.