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Selective Stimulation of C Fibers by an Intra-Epidermal Needle Electrode in Humans

机译:人体表皮内针电极对C纤维的选择性刺激

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We recorded evoked potentials (EPs) induced by intra-epidermal electrical stimulation using a needle electrode with specific parameters. We identified the fibers activated by this specific stimulation by assessing the conduction velocity (CV) of the peripheral nerve. The EPs were recorded from the Cz electrode (vertex) of the International 10-20 system in ten healthy male subjects. The dorsum of the left hand and forearm were stimulated with an intensity of 0.01 mA above the sensory threshold. The mean P1 latency of EPs for the hand and forearm were 1007 ± 88 and 783 ± 80 ms, respectively, and the CV estimated from the latency of P1 was 1.5 ± 0.7 m/s. The CV indicated that the fibers activated by the stimulation were C fibers. Since the method of stimulation is convenient and non-invasive, it should be useful for investigating the functions of small fibers.
机译:我们记录了使用特定参数的针状电极通过表皮内电刺激诱发的诱发电位(EPs)。我们通过评估周围神经的传导速度(CV)来确定由这种特定刺激激活的纤维。从国际10-20系统的Cz电极(顶点)在10名健康男性受试者中记录了EP。以高于感觉阈值0.01 mA的强度刺激左手和前臂的背部。 EP对手和前臂的平均P1潜伏期分别为1007±88和783±80 ms,根据P1潜伏期估算的CV为1.5±0.7 m / s。 CV表明受刺激激活的纤维是C纤维。由于刺激方法方便且非侵入性,因此对研究小纤维的功能应是有用的。

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