CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD); Frequency of elevated C-reactive protein in patients at Liaquat University Hospital Jamshoro/Hyderabad

摘要

Objectives: Chronic obstructive pulmonary disease (COPD) leads to partial reversible obstruction of airways. The objective of our study is to determine frequency of elevated C -reactive protein (CRP) level in patients of COPD at Liaquat University Hospital Jamshoro/Hyderabad. Study Design: Cross-sectional study. Setting: Medical Unit-I of Liaquat University Hospital Jamshoro/Hyderabad. Period: 1 st March 2013 to 31 st August 2013. Patients and Methods: Patients of either sex and ages from 40-80 years old and having COPD for at least two years duration were included. Patients below 40 years of age, having malignancies or autoimmune disorders were excluded from this study. Results: We enrolled 186 patients with COPD and their mean age was ± SD 57.63±8.45 years. Majority 182 (97.8%) had habit of smoking while 4(2.2%) were non-smokers. Mean CRP level in COPD patients was ± SD 1.26±0.79 (range 0.1- 3.0 mg/d1). Out of 186 COPD patients, 94(50.6%) have raised CRP level (higher than 1.0 mg/dl). Median value of CRP level during this study was 1.10 mg/dl. About 92(49.4%) patients have normal level of CRP (less than 1.0 mg/dl). Conclusion: On conclusion, frequency of raised C-reactive protein in our study was much higher (50.6%).