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Osteoporosis and Bone Defects in Dentistry: New Drugs and Treatment Options

机译:牙科骨质疏松症和骨缺损:新药和治疗选择

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First of all we must consider what Osteoporosis is and who is affected by it. We analyze the most common therapies (Biphosfonates, etc.) employed in this field and what their side effects are like ONJ; basically no evidence based of medicine is existing at the moment about ONJ. Patients affected by Osteoporosis and undergoing Biphosfonate therapies that need any oral surgery in general, and implant treatment in particular, could be considered as more risky patients compared with normal patients, but once again not much data is available. We verify if there are some safety precautions to take before treating these patients and if there are some procedures to avoid; considering the important rule that implant treatment should have nowadays for the quality of life of the patients. Finally, we discuss if there are existing or will be present in the future on the market some specific drugs, which would be able to increase the Osteo-integration and bone healing of patients affected by Osteoporosis.
机译:首先,我们必须考虑什么是骨质疏松症以及受其影响的人。我们分析了该领域最常用的疗法(双膦酸盐等),以及它们的副作用类似于ONJ;关于ONJ,目前基本上没有医学证据。与正常患者相比,受骨质疏松症影响并接受一般需要任何口腔外科手术且特别是植入治疗的双膦酰膦疗法的患者可被认为是风险更高的患者,但再次缺乏大量数据。我们验证在治疗这些患者之前是否需要采取一些安全预防措施,以及是否应避免某些程序;考虑到重要的规则,即当今植入物治疗应具有患者生活质量。最后,我们讨论市场上是否存在某些特定药物或将来会存在某些特定药物,这些药物将能够增强受骨质疏松症影响的患者的骨整合和骨愈合。

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