Achievements and Limits on the Controlled Release of a Drug from aTextile Fabric to Dermis

摘要

The paper presents the overall results of theoretical achievements and experimental details when designing amaterial for a textile fabric, which releases a drug for a specific pathology. It presents the conclusions of the researches onthe development of textile support as an anti-allergic, anti-fungal and anti-psoriasis type, but also on toxicological,biocompatibility and therapeutic issues for establishing the amount of drug needed for the trans-dermal diffusion. Thispaper estimates the possibility of applying a cyclodextrin (Cyc) on a textile surface to form temporary reservoirs bycomplexing and subsequently releasing the drug under the action of cutaneous stimuli. One refers to the achievements ofauthors, and works submitted by other research groups in the area of textile substrates used as implant or underwear wornnext to the skin. The results are analyzed both as a scientific communication and the possible application for a potentialcurrent industrial processing.