Dual-Integrin ?±v?23- and Gastrin-Releasing Peptide Receptor-Targeting PET Radiotracer (68Ga-BBN-RGD)

摘要

>TO THE EDITOR: Zhang and colleagues recently published their interesting work in The Journal of Nuclear Medicine (id="xref-ref-1-1" class="xref-bibr" href="#ref-1">1). Both integrin ?±_v?2₃ and gastrin-releasing peptide receptors are important markers in the biology of cancer as evidenced by the plethora of such PET radiopharmaceuticals, including arginine-glycine-aspartate (RGD) peptides for imaging angiogenesis (id="xref-ref-2-1" class="xref-bibr" href="#ref-2">2) and bombesin analogs for imaging gastrin-releasing peptide receptors (id="xref-ref-3-1" class="xref-bibr" href="#ref-3">3).