Fishing for holes in transporters: How protons breach the Na/K pump security gates

摘要

In this issue of the JGP , [Vedovato and Gadsby][1] show us that the native Na/K pumps of Xenopus laevis oocytes are even more complex machines than we realized. Readers of the JGP will be aware that Na/K pumps extrude three Na ions and import two K ions into cells with each pump cycle at the