Some Cardiovascular Risk Factors in Volunteers for health checks: A Study Of Rural And Urban Residents In The Northeast Nigeria

摘要

The prevalence rates of cardiovascular disease risk factors are increasing rapidly globally and especially so in the middle and low income countries where the adoption of Western lifestyles are considered to be responsible for the change. Our study population is drawn from sub-Saharan African communities that are also classified as low income by the WHO. In this cross sectional study we sought to use simple low cost examinations of community based individuals to determine the health burden attributable to the major cardiovascular risk factors. We studied a total of 224 volunteers of whom 102 lived in the city and 122 resided in the rural area. The male to female ratio of the study population was approximately 2:1 at the urban and 1.5:1 at the rural surveys that involved adults 18 years and older. The mean ages of the participants were 37.6 years for the urban residents and 42.8 years at the rural area. The majority did not smoke and self reported that they were involved in exercises. We identified prehypertension, hypertension, overweight and obese states, proteinuria and diabetes as the modifiable cardiovascular risk factors that occurred at high frequencies and most of which were previously undiagnosed. The prevalence rates of the risk factors were prehypertension 48 % versus 39%, hypertension 40 % versus 27 %, overweight and obese 44% versus 28 % in the urban and rural areas. There is an urgent need to combat by preventive and intervention strategies the heavy burden of cardiovascular risk factors at the community level in the Northeast of Nigeria. Introduction Cardiovascular disease is the leading cause of deaths worldwide and it was projected to account for the mortality of 17.5 million individuals globally in the year 2005 (1). Furthermore cardiovascular mortality has been projected to exceed 20 million by 2015 if the present trend in cardiovascular risk profile prevalent in the low and middle income countries is not stopped (2). Cardiovascular risk factors are rapidly expanding from the original list of the so called traditional factors such as smoking of cigarettes, male sex, high blood pressure and diabetes and cholesterol to include the more recently added ones like chronic kidney disease (3,4,5). According to Chobanian et al (6), the major cardiovascular risk factors include hypertension, older age of 55 and 65 years for men and women respectively, diabetes mellitus, elevated low density and total cholesterol concentrations. The other cardiovascular risk factors include estimated glomerular filtration rate less than 60 ml/min indicative of chronic kidney disease stage 3, microalbuminuria, obesity and cigarette smoking. The common explanation for the rising tide of cardiovascular disease worldwide is the adoption of the Western lifestyles with the resultant increase in the prevalence rates of diabetes and hypertension. Hypertension alone was responsible for 7.6 million deaths (or 13.5% of total) and 92 million or 6% of global total of Disabilty Adjusted Life Years (DALY) in the year 2001 (7). Cardiovascular disease burden is greater in developing than the developed countries where those affected are the relatively younger individuals who do not get to receive the benefit of recent advance in treatments of those conditions. Our aim in this pilot study was to use the simple, non high technology methods to determine the prevalence rates of the cardiovascular risk factors such as hypertension, proteinuria, obesity and diabetes in the urban residents who were predominantly white collar workers and to compare them with the situation prevalent in the rural dwellers who were mostly peasant farmers. Methods Cross sectional health surveys were conducted at two different locations after prior announcements of the upcoming free medical check exercises for consenting adults. The urban setting was Maiduguri while the rural setting was a remote village approximately 200 kilometers from the capital city of Borno State Nigeria. In th