Rituximab (Rituxan) Therapy for Severe Thyroid-Associated Ophthalmopathy Diminishes IGF-1R+ T Cells

Allison N. McCoy; Denise S. Kim; Erin F. Gillespie; Stephen J. Atkins; Terry J. Smith; Raymond S. Douglas

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Rituximab (Rituxan) Therapy for Severe Thyroid-Associated Ophthalmopathy Diminishes IGF-1R+ T Cells

机译：严重甲状腺相关性眼病的利妥昔单抗（Rituxan）疗法可减少IGF-1R + T细胞

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Context:Rituximab depletes CD20~(+) B cells and has shown potential benefit in thyroid-associated ophthalmopathy (TAO). The impact of rituximab on T cell phenotype in TAO is unexplored.

机译：背景：利妥昔单抗消耗CD20〜（+）B细胞，并且在甲状腺相关性眼病（TAO）中显示出潜在的益处。尚未探讨利妥昔单抗对TAO中T细胞表型的影响。

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《The journal of clinical endocrinology and metabolism》 |2014年第7期|共6页
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Allison N. McCoy; Denise S. Kim; Erin F. Gillespie; Stephen J. Atkins; Terry J. Smith; Raymond S. Douglas;
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1. Rituximab (Rituxan) Therapy for Severe Thyroid-Associated Ophthalmopathy Diminishes IGF-1R+ T Cells [J] . Allison N. McCoy, Denise S. Kim, Erin F. Gillespie, The journal of clinical endocrinology and metabolism . 2014,第7期

机译：严重甲状腺相关性眼病的利妥昔单抗（Rituxan）疗法可减少IGF-1R + T细胞
2. Targeted biological therapies for Graves' disease and thyroid-associated ophthalmopathy. Focus on B-cell depletion with Rituximab. [J] . Hegedus L, Smith TJ, Douglas RS, Clinical Endocrinology . 2011,第1期

机译：针对Graves病和甲状腺相关性眼病的靶向生物疗法。用利妥昔单抗专注于B细胞耗竭。
3. RITUXIMAB TREATMENT OF PATIENTS WITH SEVERE, CORTICOSTEROID-RESISTANT THYROID-ASSOCIATED OPHTHALMOPATHY [J] . Robert Penne Evidence-based ophthalmology . 2010,第2期

机译：利妥昔单抗治疗重症，糖皮质激素抵抗性甲状腺相关性眼病的患者
4. Characterization of a rituximab variant with potent antitumor activity against rituximab-resistant B-cell lymphoma [C] . Bohua Li, Hao Wang, Yajun Guo, International conference of molecular simulations and applied informatics technologies . 2012

机译：具有抗利妥昔单抗的B细胞淋巴瘤的有效抗肿瘤活性的利妥昔单抗变体的表征
5. Enhancing rituximab therapy: Analyzing the interaction between rituximab and the human complement pathway. [D] . Kennedy, Adam David. 2005

机译：增强利妥昔单抗治疗：分析利妥昔单抗与人类补体途径之间的相互作用。
6. Rituximab (Rituxan) Therapy for Severe Thyroid-Associated Ophthalmopathy Diminishes IGF-1R+ T Cells [O] . Allison N. McCoy, Denise S. Kim, Erin F. Gillespie, -1

机译：严重甲状腺相关性眼病的利妥昔单抗（Rituxan）疗法可减少IGF-1R + T细胞
7. Rituximab (Rituxan) Therapy for Severe Thyroid-Associated Ophthalmopathy Diminishes IGF-1R+ T Cells [O] . Allison N. McCoy, Denise S. Kim, Erin F. Gillespie, 2014

机译：Rituximab（Rituxan）治疗的严重甲状腺相关眼科病症减少了IGF-1R + T细胞

Rituximab (Rituxan) Therapy for Severe Thyroid-Associated Ophthalmopathy Diminishes IGF-1R+ T Cells

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