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首页> 外文期刊>The Internet Journal of Otorhinolaryngology >Total Thyroidectomy Versus Subtotal ThyroidectomyIn Multinodular Goitre– Our Experience
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Total Thyroidectomy Versus Subtotal ThyroidectomyIn Multinodular Goitre– Our Experience

机译:甲状腺全切除术与甲状腺全切术在多结节性甲状腺肿中的经验

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Introduction Total thyroidectomy for the management of benign Multinodular goiter is controversial and since the development of other subspecialties, it adds to further confusion. The present study aims to retrospectively compare the efficacy and morbidity of total thyroidectomy and subtotal thyroidectomy. Methods A total of 170 patients with multi nodular goiter were assigned to have either total thyroidectomy (n=100) or subtotal thyroidectomy (n=70) based on preoperative evaluation, FNAC and indications for surgery. Complications and hospital stay were also noted. Results There was no significant difference in the rate of major complications between the two procedures. There was no significant difference in distribution of post operative compl9ocations among the groups. Temporary hypoparathyroidism resulted in 37 (22%) patients in total out of which 28 (28%) belonged to total thyroidectomy group and 9 (13%) belonged to the subtotal thyroidectomy group respectively which was statistically insignificant. No permanent or temporary recurrent laryngeal nerve palsy was noted. Hematoma 2 (3%) and stitch granuloma 3 (4%) was recorded in Subtotal group. Incidental papillary carcinoma was noted in 10 (6%) patients with total thyroidectomy. Recurrence was noted in 20 (298%) of patients and 7 were taken up for further surgery and the rest managed with L-Thyroxine. 80% of the total thyroidectomies were devoid of any complications as compared to only 54.28% of subtotal Thyroidectomies without complications. Conclusion Subtotal thyroidectomy provides an unpredictable outcome and the risk of permanent complications is not less than or at par with total thyroidectomy, so there appears little or none logical reason to recommend subtotal thyroidectomy. In our experience total thyroidectomy is radical but a definitive treatment method without the risk of recurrence with a small incidence of major complications as that of a less radical procedure. Introduction Total thyroidectomy (TT) for the management of benign thyroid disorders is being increasingly accepted, although the indications are not well defined. All the treatment modalities have different types and incidences of morbidities. As a result, most surgeons have been looking for a treatment which results in the least recurrence and lowest complication rate. Many surgeons prefer Subtotal Thyroidectomy (ST) owing to the fact that the chances of permanent hypoparathyroidism are less and thought that lifelong medications are not required. As far as the fate of the recurrent laryngeal nerve is concerned, we believe the outcome varies from surgeon to surgeon. Contrary to the belief recurrence in Subtotal Thyroidectomy is not uncommon and completion surgery increases the risk of morbidity because of fibrosis. Thyromegaly apart from a neoplasia means that the gland is unable to produce enough hormones and it shows in the form of hyperplasia and after the surgery how it would be able to sustain the produce? Total thyroidectomy on the other hand, managed by total replacement therapy, has no chances of recurrence and morbidity is on par with subtotal thyroidectomy. Material & Method In the department of Otolaryngology, Pondicherry, India, a total number of 170 patients with Multinodular Goitre were considered for surgical management from Oct 2005 to Feb 2009. 160 (94%) were females and 10 (6%) were males. Age ranged from 21 to 44 years; mean age was 32.5 years ( tables 1, 2). 20 (12%) had breathing difficulties especially in the night and 80 (47%) had difficulty in swallowing ( table 3). These 100 (59%) patients with pressure symptoms were considered for total thyroidectomy and the rest 70 (41%) without pressure symptoms for subtotal thyroidectomy (table 4).All the patients were completely informed regarding the possible outcome and complications and accordingly consent was obtained. Routine blood tests, along with thyroid function tests, thyroid ultrasonography, serum calcium and fine needle aspira
机译:引言全甲状腺切除术治疗良性多结节性甲状腺肿是有争议的,并且由于其他亚专业的发展,它进一步加剧了混乱。本研究旨在回顾性比较全甲状腺切除术和甲状腺次全切除术的疗效和发病率。方法根据术前评估,FNAC和手术适应证,共170例多结节性甲状腺肿患者被分配为全甲状腺切除术(n = 100)或甲状腺全切除术(n = 70)。还注意到并发症和住院时间。结果两种手术的主要并发症发生率无明显差异。各组患者术后并发症的分布无明显差异。暂时性甲状旁腺功能减退症导致37例(22%)患者,其中28例(28%)属于全甲状腺切除术组,9例(13%)属于全甲状腺切除术组,这在统计学上无统计学意义。没有发现永久性或暂时性喉返神经麻痹。小计组记录有血肿2(3%)和缝针肉芽肿3(4%)。 10例(6%)甲状腺全切术患者发现乳头状癌。在20例(298%)的患者中发现有复发,其中7例接受了进一步手术,其余患者则使用L-甲状腺素治疗。总甲状腺切除术中有80%没有任何并发​​症,而无并发症的小计甲状腺切除术中只有54.28%。结论甲状腺全切除术提供了不可预测的结果,永久性并发症的风险不少于甲状腺全切除术或与甲状腺全切除术相当,因此几乎没有逻辑理由推荐甲状腺全切除术。根据我们的经验,全甲状腺切除术是根治性的,但是一种确定的治疗方法,没有复发的风险,主要并发症的发生率比根治性手术少。引言尽管对适应症尚无明确的定义,全甲状腺切除术(TT)用于治疗甲状腺良性疾病已日益为人们所接受。所有的治疗方式都有不同的类型和发病率。结果,大多数外科医生一直在寻找导致复发最少和并发症发生率最低的治疗方法。由于存在永久性甲状旁腺功能减退的机会较少,并且认为不需要终生药物,因此许多外科医生更喜欢进行甲状腺全切术。就喉返神经的命运而言,我们认为每个医生的结局都有所不同。与大部甲状腺切除术中复发的信念相反的是,并由于纤维化而完成手术会增加发病的风险。甲状腺肿除肿瘤外,意味着腺体无法产生足够的激素,并且以增生的形式表现出来,在手术后如何能够维持这种产生?另一方面,全甲状腺切除术,采用全替代疗法治疗,没有复发的机会,发病率与甲状腺次全切除术相当。材料与方法在印度Pondicherry的耳鼻咽喉科,从2005年10月至2009年2月,共考虑170例多结节性甲状腺肿患者进行手术治疗。女性为160(94%),男性为10(6%)。年龄从21岁到44岁不等;平均年龄为32.5岁(表1、2)。 20例(12%)呼吸困难,尤其是在夜晚,80例(47%)吞咽困难(表3)。这100例(59%)伴有压力症状的患者被认为需要全甲状腺切除术,其余70例(41%)不伴有压力症状的患者应进行甲状腺次全切除术(表4)。所有患者均被告知可能的结局和并发症,并同意获得。常规血液检查,以及甲状腺功能检查,甲状腺超声检查,血清钙和细针穿刺

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