Reduced mRNA and Protein Expression of Perilipin A and G0/G1 Switch Gene 2 (G0S2) in Human Adipose Tissue in Poorly Controlled Type 2 Diabetes

Thomas S. Nielsen; Ulla Kampmann; Roni R. Nielsen; Niels Jessen; Lotte ?rskov; Steen B. Pedersen; Jens O. J?rgensen; Sten Lund; Niels M?ller

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Reduced mRNA and Protein Expression of Perilipin A and G0/G1 Switch Gene 2 (G0S2) in Human Adipose Tissue in Poorly Controlled Type 2 Diabetes

机译：不良控制的2型糖尿病人脂肪组织中Perilipin A和G0 / G1转换基因2（G0S2）的mRNA和蛋白表达降低

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Context:Increased lipolysis and free fatty acid (FFA) levels contribute significantly to the pathogenesis of chronic and acute insulin resistance in type 2 diabetes, but the underlying mechanisms are uncertain.

机译：背景：脂解和游离脂肪酸（FFA）水平的升高在2型糖尿病的慢性和急性胰岛素抵抗的发病机理中起着重要作用，但其潜在机制尚不确定。

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《The journal of clinical endocrinology and metabolism》 |2012年第7期|共5页
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Thomas S. Nielsen; Ulla Kampmann; Roni R. Nielsen; Niels Jessen; Lotte ?rskov; Steen B. Pedersen; Jens O. J?rgensen; Sten Lund; Niels M?ller;
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1. Fasting, But Not Exercise, Increases Adipose Triglyceride Lipase (ATGL) Protein and Reduces G(0)/G(1) Switch Gene 2 (G0S2) Protein and mRNA Content in Human Adipose Tissue [J] . Thomas S. Nielsen, Mikkel H. Vendelbo, Niels Jessen, The journal of clinical endocrinology and metabolism . 2011,第8期

机译：禁食但不运动，增加人体脂肪组织中的甘油三酸酯脂肪酶（ATGL）蛋白并降低G（0）/ G（1）开关基因2（G0S2）蛋白和mRNA含量
2. Fasting, But Not Exercise, Increases Adipose Triglyceride Lipase (ATGL) Protein and Reduces G(0)/G(1) Switch Gene 2 (G0S2) Protein and mRNA Content in Human Adipose Tissue [J] . Thomas S. Nielsen, Mikkel H. Vendelbo, Niels Jessen, The journal of clinical endocrinology and metabolism . 2011,第8期

机译：禁食但不运动，增加人体脂肪组织中的甘油三酸酯脂肪酶（ATGL）蛋白并降低G（0）/ G（1）开关基因2（G0S2）蛋白和mRNA含量
3. Progesterone-induced down-regulation of hormone sensitive lipase (Lipe) and up-regulation of G0/G1 switch 2 (G0s2) genes expression in inguinal adipose tissue of female rats is reflected by diminished rate of lipolysis [J] . Stelmanska Ewa, Szrok Sylwia, Swierczynski Julian The Journal of Steroid Biochemistry and Molecular Biology . 2015,第Null期

机译：孕酮诱导的雌性大鼠腹股沟脂肪组织激素敏感性脂肪酶（Lipe）的下调和G0 / G1 switch 2（G0s2）基因表达的上调反映在脂肪分解率降低上
4. Effects of dietary protein levels and genetic background on growth and carcass performance, serum parameter, enzyme and transcription factor mRNA expression in subcutaneous adipose tissues in swine [C] . W.T.Gu, Z.Q.Liu, W.J.Tang, Progress in functional amino acids and carbohydrates for animal production . 2009

机译：日粮蛋白质水平和遗传背景对猪皮下脂肪组织生长和car体性能，血清参数，酶和转录因子mRNA表达的影响
5. The function and regulation of the G0/G1 Switch Gene 2 (G0S2). [D] . Heckmann, Bradlee Lawrence. 2016

机译：G0 / G1开关基因2（G0S2）的功能和调节。
6. Pronounced expression of the lipolytic inhibitor G0/G1 Switch Gene 2 (G0S2) in adipose tissue from brown bears (Ursus arctos) prior to hibernation [O] . Niels Jessen, Thomas S. Nielsen, Mikkel H. Vendelbo, 2016

机译：冬眠前棕熊（Ursus arctos）脂肪组织中脂解抑制剂G0 / G1开关基因2（G0S2）的明显表达
7. Reduced mRNA and Protein Expression of Perilipin A and G0/G1 Switch Gene 2 (G0S2) in Human Adipose Tissue in Poorly Controlled Type 2 Diabetes [O] . Thomas S. Nielsen, Ulla Kampmann, Roni R. Nielsen, 2012

机译：在4型糖尿病中，人脂肪组织中Perilipin A和G0 / G1切换基因2（G0S2）的MRNA和蛋白表达降低

Reduced mRNA and Protein Expression of Perilipin A and G0/G1 Switch Gene 2 (G0S2) in Human Adipose Tissue in Poorly Controlled Type 2 Diabetes

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