In the last few years, an increasing number of reports of port-site metastasis from unsuspected gallbladder cancer was published and a lot of concern has been expressed that laparoscopic cholecystectomy might adversely affect the prognosis of gallbladder cancer by increasing the risk of port-site and peritoneal seeding. The best prevention of this complication is early (preoperative) diagnosis of gallbladder cancer but this is not always possible. Cases of gallbladder carcinoma diagnosed or suspected preoperatively should be operated by open surgery rather than by laparoscopic surgery. Conversion to open cholecystectomy is appropriate if cancer is suspected during laparoscopic cholecystectomy. If gallbladder cancer is diagnosed postoperatively on histological examination of the gallbladder specimen, surgical and adjuvant radiotherapy to the trocar sites in association with extended treatment to the gallbladder bed and adjacent areas is advisable. Introduction In the last few years, an increasing number of case reports of port-site metastases following laparoscopic cholecystectomy for unsuspected carcinoma of the gallbladder was published. Concern has been expressed that laparoscopic cholecystectomy might adversely affect the prognosis of gallbladder cancer by increasing the risk of port-site and peritoneal seeding. We report three cases of port-site metastasis after laparoscopic cholecystectomy. We also review the literature for port-site metastasis from unsuspected gallbladder carcinoma.The first caseA 51-year-old male presented to the surgical outpatient department at KFMC, Riyadh, KSA, with swelling at the epigastrium for 2 months associated with yellowish discoloration of the skin and sclera and significant weight loss (17 kg in 4 months) (Fig. 1). He had had laparoscopic cholecystectomy for gallstones at another hospital 10 months before his presentation. He did not know nor had any record of the histopathology of the gallbladder.
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