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Axillary Hibernoma: An Unusual Benign Soft-Tissue Tumor

机译:腋窝纤维瘤:一种罕见的良性软组织肿瘤

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Hibernoma is an uncoomon benign tumor that comes from the vestiges of the fetal brown fat. We report the case of a 29-year-old male with a 6-month history of a painless mass in his left axilla. Due to the low incidence and prevalence in the world, we decided to present one clinical case, focusing on the clinical finding and pathology along with a review and discussion of this rare pathology. Introduction Hibernoma is a rare benign tumour consisting primarily of brown fatty tissue. It arises most often in adults from the remnants of fetal brown adipose tissue, even though not all hibernomas occur at the few sites in which brown fat is encountered in humans. It usually affects muscle and subcutaneous tissue and is asymptomatic and slow-growing. It is usually seen in locations where normal brown adipose tissue is found in foetuses and infants such as the periscapular or interscapular region, neck, axilla, inguinal region, mediastinum, periaortic and perirenal zones, and more rarely, the retroperitoneum, intrathoracic and special pleural locations1. We present a case of a hibernoma arising from the left axilla in a 29-year-old male treated by surgical resection. The diagnosis of hibernoma was only made after surgical excision, wich confirmed the presence of brown fat on histologic analysis. Clinical picture and therapeutics applied are explained. Case report A 29-year-old male presented with a mass in his left axilla which had been steadily enlarging for more than 6 months. He was totally asymptomatic. His medical history was unremarkable. Physical examination demonstrated soft-tissue fullness within the left axilla, with a mixed consistency of fatty tissue combined with a firmer, interspersed soft-tissue component. No skin changes or dimpling were present, and the left upper extremity was neurovascularly intact. Laboratory findings did not reveal anaemia or inflammatory changes. Ultrasonography demonstrated echogenic soft tissue with increased vascularity. The lesion was described on CT scan (Fig. 1), as a well-defined mass arising from the left axilla with mass effect on the surrounding structures, but without evidence of invasion of adjacent skeletal muscle. The tumour measured 9x5cm.
机译:纤维瘤良性肿瘤是胎儿棕色脂肪的残留物。我们报道了一例29岁男性,其左腋窝无痛性肿块已有6个月的历史。由于世界范围内的发病率和患病率较低,我们决定介绍一个临床病例,重点是临床发现和病理学,并对这种罕见的病理学进行回顾和讨论。简介肝癌是一种罕见的良性肿瘤,主要由褐色脂肪组织组成。尽管并非所有的冬眠瘤都发生在人类遇到褐色脂肪的少数部位,但它在成年人中最常见于胎儿褐色脂肪组织的残留。它通常会影响肌肉和皮下组织,无症状且生长缓慢。通常在胎儿和婴儿中发现正常棕色脂肪组织的位置见到,例如肩cap骨或肩cap间区域,颈部,腋窝,腹股沟区域,纵隔,腹膜周和肾周区域,很少见到腹膜后,胸腔内和特殊胸膜地点1。我们介绍了一例因手术切除而治疗的29岁男性左腋窝引起的子宫瘤。只能在手术切除后才能诊断出子宫肌瘤,并在组织学分析中证实存在棕色脂肪。解释了临床图片和治疗方法。病例报告一名29岁的男性左腋下出现肿块,并且肿块持续增大了6个月以上。他完全没有症状。他的病史不明显。体格检查显示左腋窝内软组织饱满,脂肪组织的混合稠度与更牢固的散布的软组织成分相结合。没有皮肤变化或凹陷,并且左上肢神经血管完整。实验室检查结果未显示贫血或炎症变化。超声检查显示回声软组织血管增多。病变在CT扫描上被描述(图1),是由左腋窝产生的明确肿块,对周围结构有肿块作用,但没有侵袭相邻骨骼肌的证据。肿瘤尺寸为9x5cm。

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