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Tuberculosis control in India: Refocus on nutrition

机译:印度的结核病控制:重新关注营养

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Many western societies have eliminated tuberculosis years before the advent of potent anti-tuberculous drugs, as a result of the improved standards of living and good nutrition. But even with the availability of powerful anti-tuberculous drugs, India still has a long road ahead to reach the “End TB by 2025” goal. One of the major reason is that tuberculosis control program in India till now have focused primarily on case detection and medical treatment of active tuberculosis. Drug treatment alone does not completely prevent the occurrence of new infections in the community and also contributes to development of drug resistant strains if used improperly or incompletely. Although the treatment of active cases can reduce the period of transmission of disease, a significant amount of transmission to contacts occurs even before they have been diagnosed and treated. Additionally, this approach cannot prevent re-activation to active TB in the vast pool of persons with latent TB infection. Tuberculosis occurs in those with suppressed cell mediated immunity mainly due to poor nutritional status. Improving the nutritional status of the society by several social interventions hand-in-hand with utilizing the available anti-tuberculous drugs is possibly the only effective strategy. Promising programmatic guidance for nutritional support in TB patients have been formulated by the Central TB division of India but it needs a refocusing of TB control strategies towards nutrition at all levels and strong public health actions for effective implementation.
机译:由于改善的生活水平和良好的营养,许多西方社会在有效的抗结核药物问世之前就已经消灭了结核病。但是,即使有强大的抗结核药物,印度仍要实现“到2025年实现结核病终结”目标仍任重道远。主要原因之一是,迄今为止,印度的结核病控制计划主要集中于活动性结核病的病例检测和医学治疗。如果使用不当或使用不当,仅进行药物治疗并不能完全防止社区中新感染的发生,还可能导致耐药菌株的产生。尽管对活跃病例的治疗可以减少疾病的传播时间,但即使在接触者得到诊断和治疗之前,仍会大量传播到接触者。此外,这种方法无法防止大量潜伏性结核感染患者重新激活为活动性结核。结核病发生在细胞介导的免疫力受到抑制的人群中,主要原因是营养状况不佳。通过与现有抗结核药物一起采取多种社会干预措施来改善社会的营养状况可能是唯一有效的策略。印度中央结核病司已经制定了关于结核病患者营养支持的有希望的计划性指导,但是它需要将结核病控制策略的重点重新放在各级营养上,并需要有力的公共卫生行动以有效实施。

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