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The Nano-X Linear Accelerator: A Compact and Economical Cancer Radiotherapy System Incorporating Patient Rotation

机译:Nano-X线性加速器:紧凑且经济的癌症放射治疗系统,结合患者旋转

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Rapid technological improvements in radiotherapy delivery results in improved outcomes to patients, yet current commercial systems with these technologies on board are costly. The aim of this study was to develop a state-of-the-art cancer radiotherapy system that is economical and space efficient fitting with current world demands. The Nano-X system is a compact design that is light weight combining a patient rotation system with a vertical 6 MV fixed beam. In this paper, we present the Nano-X system design configuration, an estimate of the system dimensions and its potential impact on shielding cost reductions. We provide an assessment of implementing such a radiotherapy system clinically, its advantages and disadvantages compared to a compact conventional gantry rotating linac. The Nano-X system has several differentiating features from current radiotherapy systems, it is [1] compact and therefore can fit into small vaults, [2] light weight, and [3] engineering efficient, i.e., it rotates a relatively light component and the main treatment delivery components are not under rotation (e.g., DMLCs). All these features can have an impact on reducing the costs of the system. In terms of shielding requirements, leakage radiation was found to be the dominant contributor to the Nano-X vault and as such no primary shielding was necessary. For a low leakage design, the Nano-X vault footprint and concrete volume required is 17 m2 and 35 m3 respectively, compared to 54 m2 and 102 m3 for a conventional compact linac vault, resulting in decreased costs in shielding. Key issues to be investigated in future work are the possible patient comfort concerns associated with the patient rotation system, as well as the magnitude of deformation and subsequent adaptation requirements.
机译:放射治疗技术的快速技术进步可提高患者的治疗效果,但是目前使用这些技术的商业系统成本很高。这项研究的目的是开发一种最先进的癌症放射治疗系统,该系统既经济又节省空间,可以满足当前的世界需求。 Nano-X系统结构紧凑,重量轻,将患者旋转系统与垂直6 MV固定光束结合在一起。在本文中,我们介绍了Nano-X系统的设计配置,系统尺寸的估计值及其对降低屏蔽成本的潜在影响。我们提供了一种临床上实施这种放射治疗系统的评估,与紧凑型传统龙门旋转直线加速器相比,它的优缺点。 Nano-X系统与当前的放射治疗系统有几个不同之处,它[1]紧凑,因此可以安装到小型保险库中,[2]重量轻,并且[3]工程效率高,即,它旋转了相对较轻的组件,并且主要的治疗输送组件不旋转(例如DMLC)。所有这些功能都可能对降低系统成本产生影响。在屏蔽要求方面,发现泄漏辐射是Nano-X保险库的主要贡献者,因此不需要初级屏蔽。对于低泄漏设计,与传统的紧凑型直线加速器保险库的54 m2和102 m3相比,Nano-X保险库的占地面积和所需的混凝土体积分别为17 m2和35 m3,从而降低了屏蔽成本。在未来的工作中要研究的关键问题是与患者旋转系统相关的可能的患者舒适性问题,以及变形幅度和后续适应要求。

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