Cardiovascular risk markers in a population of the Universidad Autónoma de Bucaramanga

摘要

align="justify">Introduction: Cardiovascular diseases (CVD) are the leading cause of death worldwide. In developed countries, CVD mortality has been decreasing due to the reduction of cardiovascular risk factors (CRF), but in developing countries the phenomenon is reversed. An effective way to prevent CVD is to implement strategies to identify early high-risk individuals. Objective: To study serum lipids and other markers of cardiovascular risk among employees and students of the UNAB's Medical Program. Methods: Cross sectional study which included 113 people, 59.3% women, 35.4% students. We assessed cholesterol, cholesterol-HDL, triglycerides, apolipoprotein (Apo) A1 and B using automated Imola (Randox, UK); and C-reactive protein (CRP) and interleukin-6 (IL6) by Immulite 2000 (Siemens, UK). We estimated median and interquartile range (IQR) and comparisons were made with the Wilcoxon test. Results: The age of participants ranged between 19 and 69 years, median 38 years (IQR 21-46 years). The women were younger than men (p = 0014). The older age means higher levels of markers of cardiovascular risk, cholesterol (β = 1.84 [95% CI 1.26-2.43]), triglycerides (β = 2.15 [95% CI 1.35-2.95]) and Apo B (β = 1.32 [95% CI 0.97, 1.68]). The levels of HDL and Apo A1 were higher among women, and triglycerides in men. Conclusion: Serum markers of cardiovascular risk increased progressively with age in our population, except for PCR. In women, antiatherogenic serum markers were higher compared with men. Salud UIS 2011; 43(1): 81-82.