Analysis of Inorganic Ions Levels (Calcium, Phosphate, Bicarbonate) in Saliva and Salivary Flow Rate in Periodontal Disease

摘要

Introduction : Saliva contains numerous proteins/peptides and electrolytes and therefore may serve as a source of biomarkers to monitor any changes in pathological conditions, including peridontitis. This study aimed to analyse inorganic ions levels (calcium, phosphate and bicarbonate) in saliva and the salivary flow rate in periodontal disease patients. Method : This research was analytic-observational using two groups, the healthy periodontal group consisting of 21 people (PI scores between 0-0.2) and the periodontitis group consisting of 21 people (PI scores between 0.7-8.0). Unstimulated saliva were collected using a passive drolling method. The calcium, phosphate and bicarbonate levels in the saliva were analysed using UV/Vis spectrophotometers. Results and Discussion : There was a significant difference (p=0,00) in the calcium, phosphate and bicarbonate levels between both groups and there was a relation (p=0,00) between the salivary flow rate and the levels of calcium, phospate and bicarbonate. The higher the salivary flow rate is, the greater the levels of calcium, phosphate and bicarbonate will be. Conclusion : Periodontitis caused an increase in the salivary flow rate. The increased salivary flow rate in turn increased the levels of inorganic ions in saliva such as calcium, phosphate and bicarbonate. Such events could be used as biomarkers for identifying periodontitis.