CD8+ T-Cells Expressing Interferon Gamma or Perforin Play Antagonistic Roles in Heart Injury in Experimental Trypanosoma Cruzi-Elicited Cardiomyopathy

Isabela Resende Pereira; Jaline Coutinho Silverio; Joseli Lannes-Vieira; Márcio da Costa Cipitelli; Maurício Martins Rodrigues; Nathália Ferreira Vinagre; Ricardo Tostes Gazzinelli

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CD8+ T-Cells Expressing Interferon Gamma or Perforin Play Antagonistic Roles in Heart Injury in Experimental Trypanosoma Cruzi-Elicited Cardiomyopathy

机译：表达干扰素γ或穿孔素的CD8 + T细胞在实验性锥虫克鲁兹病性心肌病的心脏损伤中起拮抗作用

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来源
《PLoS Pathogens》 |2012年第4期|共页
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Isabela Resende Pereira; Jaline Coutinho Silverio; Joseli Lannes-Vieira; Márcio da Costa Cipitelli; Maurício Martins Rodrigues; Nathália Ferreira Vinagre; Ricardo Tostes Gazzinelli;
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中图分类生物科学;
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1. Perforin and Gamma Interferon Expression Are Required for CD4+ and CD8+ T-Cell-Dependent Protective Immunity against a Human Parasite, Trypanosoma cruzi, Elicited by Heterologous Plasmid DNA Prime-Recombinant Adenovirus 5 Boost Vaccination [J] . Bruna C. G. de Alencar, Pedro M. Persechini, Filipe A. Haolla, Infection and immunity . 2009,第10期

机译：Perforin和γ干扰素表达是CD4 +和CD8 + T细胞依赖性免疫反应所必需的，该免疫反应是由异源质粒DNA重组重组腺病毒5增强的对人寄生虫克氏锥虫的免疫接种
2. Interferon-gamma plays protective roles in sodium arsenite-induced renal injury by up-regulating intrarenal multidrug resistance-associated protein 1 expression. [J] . Kimura A, Ishida Y, Hayashi T, American Journal of Pathology: Official Publication of the American Association of Pathologists . 2006,第4期

机译：干扰素-γ通过上调肾内多药耐药相关蛋白1的表达在亚砷酸钠诱导的肾损伤中发挥保护作用。
3. Differential expression of adhesion moleculesshaping the T-cell subset prevalence during the early phase of autoimmune and Trypanosoma cruzi-elicited myocarditis [J] . Ana Paula Mp Marino, Joseli Lannes-vieira, Maria Inês P Azevedo Memórias do Instituto Oswaldo Cruz . 2003,第7期

机译：在自身免疫和克氏锥虫引起的心肌炎早期，粘附分子的差异表达影响T细胞亚群的流行
4. CD8+ gamma delta regulatory T cells induced by oral exposure to alloantigen play a role in prolongation of kidney transplant survival in rats. [D] . Appleton, Sarah E. 2007

机译：口服暴露于同种抗原诱导的CD8 +γδ调节性T细胞在大鼠肾移植存活期延长中发挥作用。
5. CD8+ T-Cells Expressing Interferon Gamma or Perforin Play Antagonistic Roles in Heart Injury in Experimental Trypanosoma Cruzi-Elicited Cardiomyopathy [O] . Jaline Coutinho Silverio, Isabela Resende Pereira, Márcio da Costa Cipitelli, 2012

机译：表达干扰素γ或穿孔素的CD8 + T细胞在实验性锥虫克鲁兹诱发心肌病的心脏损伤中起拮抗作用。
6. CD8+ T-Cells Expressing Interferon Gamma or Perforin Play Antagonistic Roles in Heart Injury in Experimental Trypanosoma Cruzi-Elicited Cardiomyopathy [O] . Silverio, Jaline Coutinho, Pereira, Isabela Resende, Cipitelli, Márcio da Costa, 2012

机译：表达干扰素γ或穿孔素的CD8 + T细胞在实验性锥虫克鲁兹病性心肌病的心脏损伤中起拮抗作用

CD8+ T-Cells Expressing Interferon Gamma or Perforin Play Antagonistic Roles in Heart Injury in Experimental Trypanosoma Cruzi-Elicited Cardiomyopathy

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