Sildenafil is more selective pulmonary vasodilator than prostaglandin E(1) in patients with pulmonary hypertension due to heart failure.

摘要

In some patients, heart failure (HF) is associated with increased pulmonary vascular resistance (PVR). The magnitude and the reversibility of PVR elevation affect the HF management. Sildenafil has been recently recognized as potent PVR-lowering drug in HF