Current state?￠????of?￠????the?￠????art hyperpolarized 13 C?￠????acetate?￠????to?￠????acetylcarnitine imaging is not indicative of the altered balance between glucose and fatty acid utilization associated with diabetes

摘要

Indeed acetate trafficking matters, however, hyperpolar- ized 13 C-acetate-to-acetylcarnitine is unable to detect any significant alterations between healthy controls and type-1 diabetic rat heart, liver, and kidney, respectively in the fed state, with the current clinical setting hyperpolarized methodology.