New triterpenoid acyl derivatives and biological study of Manilkara zapota (L.) Van Royen fruits

摘要

β-amyrin-3-(3’-dimethyl) butyrate, a new natural compound was isolated from the fruits of Manilkara zapota (L.) Van Royen, in addition to lupeol-3-acetate and 4-caffeoylquinic acid (cryptochlorogenic acid). The structures of these compounds were identified using different spectral methods (IR, MS, UV, 1H-NMR, 13C-NMR and 2D-NMR). The alcoholic and aqueous extracts of the unripe fruits, in addition to their aqueous homogenate exhibited antioxidant, antihyperglycemic and hypocholesterolemic activities.Keywords: 4-caffeoylquinic acid, antihyperglycemic, antioxidant, β-amyrin-3-(3’-dimethyl)butyrate, hypocholesterolemic, lupeol-3-acetate, Manilkara zapota