To achieve optimal therapy of antibiotics isonefactor supporting the accuracy in prescribing antibiotics errors in prescribing can cause lack of rationality in the use of antibiotics . Antibiotic was commonly used in the clinicor in private practice doctors but also in the centers of other health services such as polyclinics and hospitals the aim of this study is to assess antibiotic prescribing patterns and the level of rationality the use of antibiotics in adult patients at one center of Yogyakarta on the basis of data prescriptions. This Study used descriptive design with retrospective data collection The data was collected from January to April 2010 Data source is a prescription of antibiotics in adult patients We analyzed the antibiotics prescription in the study based on the selection appropriate dos age frequency and duration. We recruited 320 patients receive ing antibiotics. The of antibiotics used were amoxicillin 64.5 % ampicillin 11.3 % kontrimoksazol 15.9% chloramphenicol 0.6 % metronidazole 2.8 % and etracycline 49 % Most of the Patients received a single antibiotic 97.9 %), while the remaining patients received a combination of antibiotics 2.1 % All prescribing meet appropriate dosage, and frequency except cotrimoxazole (98%) and ampicillin 49%). All prescriptions (100%) improper duration. In general antibiotics prescription for adult patients at one health center in Yogyakarta City is comply with the standard use of antibiotics in Public Health Centers. However, the duration of antibiotic utilization still became the perspective of the health providers in Public Health Centers.
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