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首页> 外文期刊>Pesquisa Veterinária Brasileira >Sodium bicarbonate as prevention of metabolic acidosis in sheep submitted to experimental ruminal acidosis
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Sodium bicarbonate as prevention of metabolic acidosis in sheep submitted to experimental ruminal acidosis

机译:碳酸氢钠预防羊代谢性酸中毒

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The aim of this study was to evaluate the preventive effect of sodium bicarbonate on systemic acidosis due to ruminal acidosis, which was induced by ingestion of concentrate after prolonged fasting. Fourteen sheep were divided into three experimental groups: control group (Cg), with four sheep, submitted to fasting without development of ruminal acidosis; no-treated group (NTg), with five sheep with rumen acidosis without preventive treatment; and treated group (Tg), with five sheep with rumen acidosis and preventively treated with sodium bicarbonate. Assessments of ruminal pH and arterial hemogasometry were performed for 48 hours after ingestion of the concentrate. There was a reduction in the ruminal pH in all groups, whereas the Cg showed a reduction only after 24 hours. A reduction in the arterial pH, bicarbonate and base excess in all groups was also noted, indicating systemic metabolic acidosis, but the NTg presented the greatest alteration. It is concluded that sodium bicarbonate prevents systemic metabolic acidosis, reducing its severity in sheep subjected to ruminal acidosis.
机译:这项研究的目的是评估碳酸氢钠对瘤胃酸中毒的系统性酸中毒的预防作用,瘤胃酸中毒是由于长期禁食后摄入浓缩液而引起的。将十四只绵羊分为三个实验组:对照组(Cg),有四只绵羊,禁食而没有瘤胃酸中毒;未治疗组(NTg),有五只绵羊瘤胃酸中毒,未经预防;治疗组(Tg),其中5只绵羊瘤胃酸中毒并用碳酸氢钠预防性治疗。摄入精矿后48小时进行瘤胃pH值和动脉血压测定。所有组的瘤胃pH均降低,而Cg仅在24小时后才降低。还注意到所有组的动脉pH,碳酸氢根和碱过量的减少,表明全身性代谢性酸中毒,但是NTg表现出最大的改变。结论是,碳酸氢钠可预防全身性代谢性酸中毒,从而降低遭受瘤胃酸中毒的绵羊的严重程度。

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