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Quality of veterinary pharmaceuticals and their use by pastoralists in the Far North Region of Cameroon

机译:喀麦隆极北地区兽药的质量及其牧民的使用

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摘要

This study evaluates the quality of the veterinary drugs most frequently used in the Far North Region of Cameroon and describes how pastoralists use them to treat their cattle herds. High-performance liquid chromatography was used to identify and quantify the active ingredients in the drugs (penicillin G, levamisole, oxytetracycline, diminazene diaceturate, vitamin A, and vitamin E acetate) and gas chromatography mass spectrometry to determine if organic chemical contaminants were present. The results showed that 69% of surveyed pastoralists used veterinary medicines to treat common illnesses. In addition, the most commonly used medications (procaine penicillin G and oxytetracycline) were used in a manner inconsistent with the recommended dosage, frequency, duration, and withdrawal period by 98% of the pastoralists. However, contrary to previous studies, the quality of the medications used by pastoralists was generally good. The poor compliance with recommended treatment protocols was much more prevalent than use of poor quality medications and presents a potential for treatment failure, drug resistance of animal pathogens, and harmful drug residues in the human food supply, all of which have potentially negative consequences for animal and human health.
机译:这项研究评估了喀麦隆远北地区最常用的兽药质量,并描述了牧民如何使用它们来治疗牛群。高效液相色谱法用于鉴定和定量药物中的活性成分(青霉素G,左旋咪唑,土霉素,双米氮烯二乙酸酯,维生素A和乙酸维生素E)和气相色谱质谱法,以确定是否存在有机化学污染物。结果表明,接受调查的牧民中有69%使用兽药治疗常见疾病。此外,98%的牧民以最不推荐的剂量,频率,持续时间和停药期使用了最常用的药物(普鲁卡因青霉素G和土霉素)。但是,与以前的研究相反,牧民使用的药物质量总体良好。与推荐的治疗方案的依从性较差,比使用质量较差的药物更为普遍,并且存在治疗失败,动物病原体的耐药性以及人类食物供应中有害药物残留的可能性,所有这些因素均会对动物产生负面影响和人类健康。

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