Therapeutic Effects of Restricted Diet in Obese Patients with Non-Alcoholic Fatty Liver Disease (NAFLD)

摘要

Objective: In this study, the effect of restricted diet in obese patients with Non-Alcoholic Fatty Liver Disease (NAFLD) was evaluated. Design: A convenient, clinical trials study (before and after) with 6 weeks treatment period. Subjects: Forty NAFLD patients (15 men and 25 women) with mean age 45.8±7.6 years were selected among the patient referred to gastroenterology clinic of Motahary Center. Setting: Patients selection was based on BMI > 25 kg/m2 and NAFLD patient. Anthropometric indices were measured and BMI was calculated. A food frequency questionnaire was collected before and after consumption of diet containing 12-15% protein, 25-30% fat and 55-60% carbohydrate. A fasting blood sample for measuring LFT were collected at the beginning and after 6 weeks consumption of low fat and low calorie diet. Result: There were statistically significant decrease in mean body weight (p Conclusions: These findings suggest that consumption of low fat, low caloric diet for 6 weeks in obese patient with NAFLD have a positive effect on body weight, BMI and it improves blood glucose lipids and LFT profile.