0032 Identification Of A Muscle Function Protein In Brain Through A Proteomic Screen In Identification Of A Muscle Function Protein In Brain Through A Proteomic Screen In Sleep-deprived Mice

摘要

IntroductionRecently, we identified that a clock protein in skeletal muscle has the ability to alter recovery responses to sleep deprivation, presenting evidence for a muscle-brain axis of sleep regulation (Ehlen et al. 2017). Here, we continue a search for mechanism of action through a proteomic screen in C57BL/6J mice (same background as Ehlen et al. 2017).