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A surgical case of radiotherapy induced esophageal perforation accompanying pyogenic spondylodiscitis: a case report

机译:放射治疗诱发化脓性脊椎炎并发食管穿孔的外科病例:病例报告

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Background Stereotactic body radiotherapy has been a treatment choice for lung cancer, especially in medically inoperable patients. However, the acute and late toxicity to adjacent organs have been reported as an uncommon but severe adverse effect. Case presentation A 65-year-old male was presented with his back pain and pyrexia. He had been followed up for non-small-cell lung cancer, which was treated by the stereotactic body radiotherapy 4?years prior to the current visit. The endoscopy revealed an esophageal perforation on its left side in the upper thoracic locus. Because of his poor lung function, he was managed by the conservative treatment. After 3?months, his back pain recurred with developing paraplegia in the lower extremities. The MRI revealed an abscess formation at the posterior side of the upper thoracic esophagus which destroyed the vertebral body and compressed the spinal cord. Laminectomy and two-stage operation—the first stage, nontransthoracic esophagectomy, cervical and transhiatal approach using mediastinoscope and laparoscope, and the second stage, esophageal reconstruction—were performed. Conclusion This complex disease status was successfully managed by the orthopedic surgery followed by a two-stage esophagectomy without transthoracic approach.
机译:背景技术立体定向放射疗法一直是肺癌的治疗选择,特别是在无法手术的患者中。然而,据报道对邻近器官的急性和晚期毒性是一种罕见但严重的不良反应。病例介绍一名65岁的男性因背部疼痛和发热而出现症状。对他进行了非小细胞肺癌的随访,该肺癌在本次就诊前4年通过立体定向放射疗法进行了治疗。内窥镜检查显示在上胸位的左侧有食管穿孔。由于他的肺功能差,他接受了保守治疗。 3个月后,他的下肢复发性截瘫再次出现。 MRI显示上胸食道后侧有脓肿形成,破坏了椎体并压迫了脊髓。进行了椎板切除术和两个阶段的手术​​-第一阶段,非经胸食管切除术,使用纵隔镜和腹腔镜的宫颈和经食道入路,第二阶段,食管重建。结论这种复杂的疾病状态可以通过整形外科手术,然后经无胸腔入路的两阶段食管切除术来成功处理。

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