A large retroperitoneal lymphatic malformation successfully treated with traditional Japanese Kampo medicine in combination with surgery

摘要

BackgroundCurrent treatment options for lymphatic malformations (LMs) are multimodal. Recently, the effectiveness of treating LMs with Eppikajyutsuto (TJ-28) has been reported. TJ-28 is a kind of oral herbal medicine classified as the traditional Japanese Kampo medicine. Case presentationA 12-year-old girl was admitted to our hospital for intermittent upper abdominal pain. Radiological examinations revealed a large (9.5?×?5.8?×?10.0?cm) retroperitoneal LM, which was suspected to adhering and stretching both pancreas head and duodenum. The large retroperitoneal tumor resection might induce involving complications because of the size and the location. Therefore, we used TJ-28 in order to diminish the tumor size before surgery. The patient received oral doses of 7.5?g/day (2.5?g?×?3 times/day) of TJ-28. Six months after the medication, the tumor decreased markedly to 3.5?×?1.5?×?1.2?cm in size. Thereafter, the mass was sub-totally resected (95%) via a 3?cm trans-umbilical incision without any surgical complications. ConclusionsWe reported a case of successfully treated retroperitoneal LM with the combination treatment of TJ-28 and surgery. Based on our experience, this TJ-28 treatment option may be very useful in treating cases of LMs having surgical difficulties because of size and/or location.