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Soroepidemiologia da infec??o pelo vírus da hepatite A em 'meninos dea rua' de Goiania-Goiás

机译:戈亚尼亚-戈亚斯州“街头男孩/街头男孩”中的甲型肝炎病毒血清流行病学

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摘要

A cross-sectional study was performed to determine the age-prevalence of hepatitis A virus CHAV) among street youth from Goiania city - Central Brazil, and to determine if any risk factors could be identified. The surveys were conducted between 1991/1992. The street youth were 397 individuals aged 7 to 21 years old living in institutions and teenagers working at streets. Then, 313 adolescents working at streets and with family links, and 84 institutionalized ones without family were screened for antibodies against HAV. Prevalences ranged from 80.0% to 92.2% to total anti-HAV and there was not a statistically significant trend ofpositivity with age in this group. Unvariate analysis for risk factors associated with HAV infection was performed with no statistically significant difference for adolescents working at streets and living with parents, and street youth with family links. Economic variables were not statistically associated with seropositivity, probable due to homogenous characteristics of the group. This study disclosed that street youth have a high rate of HAV infection. These findings do not suggest differences between subgroups of populations in acquiring immunity to HVA. The public health implication and the need of screening other subgroups of population of the same city were suggested in order to discuss vaccine strategy in underdeveloped countries.
机译:进行了一项横断面研究,以确定来自巴西中部戈亚尼亚市的街头青年中甲型肝炎病毒(CHA)的年龄患病率,并确定是否可以确定任何危险因素。这些调查是在1991/1992年之间进行的。街头青年有397人,年龄在7-21岁之间,居住在机构中,在街头工作的青少年。然后,筛选了313名在街头和有家庭联系的青少年以及84个没有家庭的寄养青少年,以寻找抗HAV的抗体。总体抗-HAV的患病率从80.0%到92.2%不等,该年龄组的阳性率没有统计学上的显着趋势。对与在街上工作和与父母同住的青少年以及与家庭有联系的街头青年,进行了与HAV感染相关的危险因素的无统计学分析,差异无统计学意义。经济变量与血清阳性没有统计学联系,这可能是由于该组的同质性所致。这项研究表明,街头青年有很高的HAV感染率。这些发现并不表明在获得针对HVA的免疫力方面人群的亚组之间存在差异。为了讨论欠发达国家的疫苗战略,建议了公共卫生的含义以及对同一城市其他人群进行筛查的需要。

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