Synthesis and Antimicrobial Studies of Tridentate Schiff Base Ligands with Pyrazolone Moiety and Their Metal Complexes

摘要

Synthesis, characterization, and antimicrobial activity of tridentate Schiffbase ligands containing pyrazolone moiety (3aand3b) and their transition metal complexes of VO(II), Cu(II), Fe(III), and Co(II)4a–hhave been investigated. The complexes show enhanced antibacterial activity againstS. aureus, E. coli, and S. typhiand antifungal activity againstC. albicans, Rhizopus sp., and A. nigercompared to the ligands.