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Myxopapillary Ependymoma of the III Ventricle: Example of a Histological Variant of Ependymoma with Exceptional Localization

机译:III心室的黏膜乳头状室室管膜瘤:局限性室管膜瘤的组织学变异的示例

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We present morphological findings observed from the study of a myxopapillary ependymoma located in the III ventricle. This tumor, which is a rare occurrence at this level, was observed in a 73-year-old woman with no relevant medical history who presented with obstructive hydrocephalus due to compression and blockage of the foramen of Monro. The good delineation of the lesion allowed its surgical excision, and histological examination of the material obtained after excisional biopsy revealed a glial neoplasm with a low degree of cytological malignancy that was strongly positive for glial fibrillary acidic protein (GFAP) as well as a myxopapillary architecture analogous to that observed in ependymomas of the filum terminale. Subsequent radiological examination allowed us to rule out a metastatic nature of the tumor, confirming its primary origin. We briefly discuss the case and review the main characteristics of this neoplasia, which is quite rare at the site identified in our patient.
机译:我们提出了从位于第三脑室的黏膜乳头状室膜瘤的研究中观察到的形态学发现。在没有相关病史的73岁妇女中,该肿瘤在此水平上很少发生,该妇女由于门罗的孔被挤压和阻塞而出现阻塞性脑积水。病变的良好轮廓允许其进行手术切除,并且对切除活检后获得的材料的组织学检查显示,具有低细胞学恶性程度的神经胶质瘤对神经胶质纤维酸性蛋白(GFAP)和粘膜乳头状结构强烈阳性类似于在terminal的室管膜瘤中观察到的。随后的放射学检查使我们可以排除肿瘤的转移性质,从而确认其主要起源。我们简要讨论该病例并回顾这种瘤形成的主要特征,这种现象在我们患者中确定的部位非常罕见。

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