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首页> 外文期刊>Oftal mokhirurgiya >ФЕМТОЛАЗЕРНАЯ ПЕРЕДНЯЯ ПОСЛОЙНАЯ КЕРАТОПЛАСТИКА: ПИЛОТНОЕ КЛИНИЧЕСКОЕ ИССЛЕДОВАНИЕ
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ФЕМТОЛАЗЕРНАЯ ПЕРЕДНЯЯ ПОСЛОЙНАЯ КЕРАТОПЛАСТИКА: ПИЛОТНОЕ КЛИНИЧЕСКОЕ ИССЛЕДОВАНИЕ

机译:FEMTOLASER层状角膜塑形术:初步临床研究

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Purpose. To work out a technology of a femtosecond laser assisted anterior lamellar keratoplasty and evaluate its safety and clinical efficiency. Material and м ethods. We report 13 cases of femtosecond laserassisted anterior lamellar keratoplasty. Both circular trepanation and lamellar dissection (80% of the corneal thickness) were performed with the IntraLase FS 60 kHz (AMO). Lamellar cut settings for the donor cornea were: spot/line separation 4/4μm, energy 1μJ; for the recipient 4/4μm and 2μJ, respectively. Eyes of 13 patients (11 with keratoconus, 2 with superficial corneal scarring) in the mean age 30.3±9.5 years were observed up to 2 year s after the surgery. Results. All corneal grafts were transparent, with the mean endothelial cell loss at 12 months equal to 3.5%. Evaluation of biomechanical properties of patients’ corneas 1 year after the surgery showed a reliable improvement of the CRF and CH meanings, comparable to preoperative data, from 5.7±1.28 and 6.92±1.32mmHg to 10.92±1 and 10.61±1.3mmHg (p&0.001), respectively, which correlates with the rates of normal cornea. Sutures were removed 6 months after surgery. The mean postoperative astigmatism at 12 months was 4.7±1.5 D. The mean UCVA at 12 months was 0.1±0.02 and the BCVA was 0.22±0.07. After 2 years the values were 0.2±0.03 and 0.3±0.05, respectively. The highest BCVA was achieved0.4 in 2 cases at 12 months. Conclusions. The obtained low postoperative visual acuity is explained, apparently, by irregularities of the donor-recipient interface and a pronounced light scattering occurred in it which leads to a reduction of the retinal image quality.
机译:目的。拟定飞秒激光辅助前板层角膜移植术的技术,并评估其安全性和临床疗效。材料和方法。我们报告13例飞秒激光辅助的前板层角膜移植手术。使用IntraLase FS 60 kHz(AMO)进行圆环切开术和层状解剖(角膜厚度的80%)。供体角膜的层状切割设置为:点/线间隔4 /4μm,能量1μJ;分别为4 /4μm和2μJ。术后2年内,平均年龄30.3±9.5岁的13例患者的眼睛(11例圆锥角膜,2例表面角膜瘢痕)。结果。所有角膜移植物都是透明的,在12个月时平均内皮细胞损失等于3.5%。术后1年对患者角膜生物力学性能的评估显示,与术前数据相比,CRF和CH的含义得到了可靠的改善,从5.7±1.28和6.92±1.32mmHg降至10.92±1和10.61±1.3mmHg(p 0.001),分别与正常角膜的发生率相关。手术后6个月将缝线移除。 12个月时的平均术后散光为4.7±1.5D。12个月时的平均UCVA为0.1±0.02,BCVA为0.22±0.07。 2年后,该值分别为0.2±0.03和0.3±0.05。在12个月的2例中,最高BCVA达到0.4。结论。显然,术后供体视敏度低是由于供体-受体界面不规则,并且在其中出现明显的光散射,导致视网膜图像质量下降。

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