SYNTHESIS OF SOME1,4,5-TRISUBSTITUTED 1,2,3-TRIAZOLES BY 1,3-DIPOLAR CYCLOADDITION OF 2-SUBSTITUTED PHENYL AZIDES TO DIMETHYL ACETYLENE DICARBOXYLATE (DMAD), REGULAR STIRRING VERSUS MICROWAVE IRRADIATION:A COMPARATIVE STUDY

摘要

1,4,5-trisubstituted 1,2,3-triazoles were prepared by 1,3-dipolar cycloaddition reaction of some 2-substituted phenyl azides to dimethylacetylene dicarboxylate (DMAD) under regular stirring at room temperature or under microwave irradiation. The targeted compounds were obtained in good to excellent yields. The use of microwave irradiation gives the highest yields in few minutes and proper products.