We report a case of a 46-year-old woman without any medical history who presented to our Respiratory Department with exertional dyspnoea for the last 6 weeks associated with non-productive cough. Chest radiography showed bilateral diffuse interstitial opacity. Bronchoalveolar lavage and transbronchial biopsies performed during flexible bronchoscopy as a step in the diagnostic workup of idiopathic interstitial pneumonia showed cells of pulmonary adenocarcinoma. Highlights ? Diffuse interstitial infiltrates have numerous differential diagnoses. ? Malignancy is one of the important differential diagnoses and should not be missed. ? Pathological samples have a crucial role in the diagnostic work-up of interstitial opacities.
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