Administration of Bacillus subtilis C-3102 (Calsporin?) may improve feces consistency in dogs with chronic diarrhea

摘要

The influence of supplemental Bacillus subtilis C - 3102 on chronic diarrhea was studied in 40 privately - owned dogs subjected to a double - blind, placebo - controlled trial. After a run - in period of one week, 20 dogs received eith er placebo or test tablets for four weeks. Test tablets contained 1.3 x 10 8 colony forming units (CFU) Bacillus subtilis C - 3102 per tablet. Both supplements were administered at a rate of half a tablet per 100 g of air - dry habitual diet, which equals 100 p pm Calsporin in the diet. The owners scored fecal characteristics on a line from 0 to 10 cm. For each dog and each variable, the change over time versus baseline was calculated. In comparison with the control treatment, ad ministration of the probiotic did not influence fecal consistency, color and appearance of blood and mucus. The probiotic significantly improved fecal odor (P = 0.037) and tended to reduce flatulence incidence (P = 0.082) and apparent fecal fermentation (P = 0.080). There was no treatment effect on the degree of tenesmus, failed defecation, fecal volume and coprophagy. The probiotic tended to improve coat condition (P = 0.058). Dogs with higher severity degrees of diarrhea during the run - in period showed more improvement during the test per iod (P = 0.002), this relationship being clearly perceptible for the dogs receiving probiotic treatment (P = 0.056). It is co ncluded that administration of Bacillus subtilis C - 3102 is an effective adjuvant therap y to the treatment of chronic diarrhea in do gs. It is suggested that a well - formulated dog food supplemented with Bacillus subtilis C - 3102 may optimall y support fecal and coat quality.